학술논문
Nitroxide Synthase Activity as a Marker of Early Stages of Experimental Cartilage Dysmetabolism
Document Type
Article
Source
Bulletin of Experimental Biology and Medicine; May 2004, Vol. 137 Issue: 5 p517-520, 4p
Subject
Language
ISSN
00074888; 15738221
Abstract
Time course of nitroxide synthase activity in the knee joint cartilage was studied in animals with experimental anterior instability of the knee joint. A significant increase in nitroxide synthase activity in chondrocytes was paralleled by a progressive decrease in glycosaminoglycan content in the cartilaginous matrix and subsequent destruction of the cartilage cytoarchitectonics.