학술논문
Nutritional deficiency amblyopia or Leber's hereditary optic neuropathy?
Document Type
Article
Author
Source
Neuro-Ophthalmology; October 1997, Vol. 18 Issue: 3 p111-116, 6p
Subject
Language
ISSN
01658107; 1744506X
Abstract
A 45-year-old man presented with progressive bilateral painless central visual loss. He had a history of alcohol abuse and no family history of visual impairment. The patient was initially diagnosed as having nutritional deficiency amblyopia (NDA), but visual deterioration continued despite a balanced diet and high potency B vitamin supplementation. Ultimately, mitochondrial DNA analysis was positive for the 11778 mutation of Leber's hereditary optic neuropathy (LHON).