학술논문
Neutralizing antibodies against SARS-CoV-2 variants following mRNA booster vaccination in adults older than 65 years
Document Type
Original Paper
Author
Durier, Christine; Ninove, Laetitia; Lefebvre, Maeva; Radenne, Anne; Desaint, Corinne; Ropers, Jacques; Bauer, Rebecca; Lebbah, Said; Carette, Diane; Lachatre, Marie; Lecompte, Anne-Sophie; Deplanque, Dominique; Botelho-Nevers, Elisabeth; Conrad, Anne; Dussol, Bertrand; Maakaroun-Vermesse, Zoha; Melica, Giovanna; Nicolas, Jean-François; Verdon, Renaud; Kiladjian, Jacques; Loubet, Paul; Schmidt-Mutter, Catherine; Dualé, Christian; Ansart, Séverine; Priet, Stéphane; Levier, Axel; Molino, Diana; Vieillard, Louis-Victorien; Parfait, Béatrice; Lelièvre, Jean-Daniel; Tartour, Eric; de Lamballerie, Xavier; Launay, Odile
Source
Scientific Reports. 12(1)
Subject
Language
English
ISSN
2045-2322
Abstract
Immune response induced by COVID-19 vaccine booster against delta and omicron variants was assessed in 65 adults (65–84 years old) early aftesr a first booster dose. An increase in SARS-CoV-2 neutralizing antibodies was shown in individuals not previously infected without evidence of an age-related effect, with lower increase in those infected before a single dose of primary vaccination. Of note, humoral response was observed only starting from the 5th day after the boost.