학술논문
Long-term exposure to air pollution and severe COVID-19 in Catalonia: a population-based cohort study
Document Type
Original Paper
Author
Ranzani, Otavio; Alari, Anna; Olmos, Sergio; Milà, Carles; Rico, Alex; Ballester, Joan; Basagaña, Xavier; Chaccour, Carlos; Dadvand, Payam; Duarte-Salles, Talita; Foraster, Maria; Nieuwenhuijsen, Mark; Sunyer, Jordi; Valentín, Antònia; Kogevinas, Manolis; Lazcano, Uxue; Avellaneda-Gómez, Carla; Vivanco, Rosa; Tonne, Cathryn
Source
Nature Communications. 14(1)
Subject
Language
English
ISSN
2041-1723
Abstract
The association between long-term exposure to ambient air pollutants and severe COVID-19 is uncertain. We followed 4,660,502 adults from the general population in 2020 in Catalonia, Spain. Cox proportional models were fit to evaluate the association between annual averages of PM2.5 , NO2 , BC, and O3 at each participant’s residential address and severe COVID-19. Higher exposure to PM2.5, NO2, and BC was associated with an increased risk of COVID-19 hospitalization, ICU admission, death, and hospital length of stay. An increase of 3.2 µg/m3 of PM2.5 was associated with a 19% (95% CI, 16–21) increase in hospitalizations. An increase of 16.1 µg/m3 of NO2 was associated with a 42% (95% CI, 30–55) increase in ICU admissions. An increase of 0.7 µg/m3 of BC was associated with a 6% (95% CI, 0–13) increase in deaths. O3 was positively associated with severe outcomes when adjusted by NO2 . Our study contributes robust evidence that long-term exposure to air pollutants is associated with severe COVID-19.
In this study, the authors investigate the relationship between exposure to air pollutants and severe COVID-19 disease using data from a cohort of ~5 million people in Catalonia, Spain. They find that long-term exposure to pollutants is associated with a higher risk of COVID-19-related hospitalization, death, intensive care admission, and length of hospital stay.
In this study, the authors investigate the relationship between exposure to air pollutants and severe COVID-19 disease using data from a cohort of ~5 million people in Catalonia, Spain. They find that long-term exposure to pollutants is associated with a higher risk of COVID-19-related hospitalization, death, intensive care admission, and length of hospital stay.