학술논문

Mapping functional connectivity of bursting neuronal networks
Document Type
Original Paper
Source
Applied Network Science. December 2017 2(1):1-10
Subject
Calcium imaging
Laser scanning photostimulation
Neuronal network
Network bursting
Language
English
ISSN
2364-8228
Abstract
Using single-cell laser scanning photostimulation (LSPS) combined with broad-field calcium imaging, we measured the functional connectivity of neuronal cultures before and after the developmental appearance of network bursting. From these data, network properties were determined for these relatively large neuronal networks. Based on these properties, we found that although ‘small-world’ network behavior existed throughout this time period, only average node degree and global efficiency correlate with the development of network bursting while clustering and local efficiency remained relatively constant.