학술논문
Expert consensus on the diagnosis and treatment of end-stage liver disease complicated by infections
Document Type
Editorial Notes
Author
Chen, Tao; Chen, Guang; Wang, Guiqiang; Treeprasertsuk, Sombat; Lesmana, Cosmas Rinaldi Adithya; Lin, Han-Chieh; Al-mahtab, Mamun; Chawla, Yogesh K.; Tan, Soek-Siam; Kao, Jia-Horng; Yuen, Man-Fung; Lee, Guan-Huei; Alcantara-Payawal, Diana; Nakayama, Nobuaki; Abbas, Zaigham; Jafri, Wasim; Kim, Dong-Joon; Choudhury, Ashok; Mahiwall, Rakhi; Hou, Jinlin; Hamid, Saeed; Jia, Jidong; Bajaj, J. S.; Wang, Fusheng; Sarin, Shiv K.; Ning, Qin
Source
Hepatology International. :1-16
Subject
Language
English
ISSN
1936-0533
1936-0541
1936-0541
Abstract
End-stage liver disease (ESLD) is a life-threatening clinical syndrome and when complicated with infection the mortality is markedly increased. In patients with ESLD, bacterial or fungal infection can induce or aggravate the occurrence or progression of liver decompensation. Consequently, infections are among the most common complications of disease deterioration. There is an overwhelming need for standardized protocols for early diagnosis and appropriate management for patients with ESLD complicated by infections. Asia Pacific region has the largest number of ESLD patients, due to hepatitis B and the growing population of alcohol and NAFLD. Concomitant infections not only add to organ failure and high mortality but also to financial and healthcare burdens. This consensus document assembled up-to-date knowledge and experience from colleagues across the Asia–Pacific region, providing data on the principles as well as evidence-based current working protocols and practices for the diagnosis and treatment of patients with ESLD complicated by infections.