학술논문

Building Programs to Eradicate Toxoplasmosis Part IV: Understanding and Development of Public Health Strategies and Advances “Take a Village”
Document Type
Review Paper
Author
Felín, Mariangela SoberónWang, KanixMoreira, AliyaGrose, AndrewLeahy, KarenZhou, YingClouser, Fatima AlibanaSiddiqui, MaryamLeong, NicoleGoodall, PerpetuaMichalowski, MorganIsmail, MahmoudChristmas, MonicaSchrantz, StephenCaballero, ZuleimaNorero, XimenaEstripeaut, DoraEllis, DavidRaggi, CatalinaCastro, CatherineMoossazadeh, DavinaRamirez, MargaritaPandey, AbhinavAshi, KevinDovgin, SamanthaDixon, AshtynLi, XuanBegeman, IanHeichman, SharonLykins, JosephVillalobos-Cerrud, DelbaFabrega, LorenaMontalvo, José Luis SanchezMendivil, ConnieQuijada, Mario R.Fernández-Pirla, Silviade La Guardia, ValliWong, Dignade Guevara, Mayrene LadrónFlores, CarlosBorace, JovannaGarcía, AnabelCaballero, NatividadRengifo-Herrera, Claudiade Saez, Maria Theresa MorenoPolitis, MichaelRoss, StephanieDogra, MimansaDhamsania, VishanGraves, NicholasKirchberg, MarciMathur, KopalAue, AshleyRestrepo, Carlos M.Llanes, AlejandroGuzman, GermanRebellon, ArturoBoyer, KennethHeydemann, PeterNoble, A. GwendolynSwisher, CharlesRabiah, PeterWithers, ShawnHull, TeriFrim, DavidMcLone, DavidSu, ChunleiBlair, MichaelLatkany, PaulMui, ErnestVasconcelos-Santos, Daniel VitorVillareal, AlcibiadesPerez, AmbarGalvis, Carlos Andrés NaranjoMontes, Mónica VargasPerez, Nestor Ivan CardonaRamirez, MorganChittenden, CyWang, EdwardGarcia-López, Laura LorenaPadrieu, GuillermoMuñoz-Ortiz, JulianaRivera-Valdivia, NicolásBohorquez-Granados, María Cristinade-la-Torre, Gabriela CastañoHernandez, Juan David ValenciaCelis-Giraldo, DanielDávila, Juan Alejandro AcostaTorres, ElizabethOquendo, Manuela MejiaArteaga-Rivera, José Y.Nicolae, Dan LRzhetsky, AndreyRoizen, NancyStillwaggon, EileenSawers, LarryPeyron, FrancoisWallon, MartineChapey, EmanuelleLevigne, PaulineCharter, CarmenDe Frias, MigdaliaMontoya, JosePress, CindyRamirez, RaymundContopoulos-Ioannidis, DespinaMaldonado, YvonneLiesenfeld, OliverGomez, CarlosWheeler, KelseyZehar, SamanthaMcAuley, JamesLimonne, DenisHouze, SandrineAbraham, SylviePiarroux, RaphaelTesic, VeraBeavis, KathleenAbeleda, AnaSautter, MariEl Mansouri, BouchraEl Bachir, AdlaouiAmarir, FatimaEl Bissati, KamalHolfels, EllenFrim, DavidMcLone, DavidPenn, RichardCohen, Williamde-la-Torre, AlejandraBritton, GabrielleMotta, JorgeOrtega-Barria, EduardoRomero, Isabel LuzMeier, PaulGrigg, MichaelGómez-Marín, JorgeKosagisharaf, Jagannatha RaoLlorens, Xavier SáezReyes, OsvaldoMcLeod, Rima
Source
Current Pediatrics Reports. 10(3):125-154
Subject
congenital toxoplasmosis
diagnostic testing
prenatal screening
point-of-care testing
antiparasitic treatment
marginalized populations
Language
English
ISSN
2167-4841
Abstract
Purpose of Review: Review international efforts to build a global public health initiative focused on toxoplasmosis with spillover benefits to save lives, sight, cognition and motor function benefiting maternal and child health.Recent Findings: Multiple countries’ efforts to eliminate toxoplasmosis demonstrate progress and context for this review and new work.Summary: Problems with potential solutions proposed include accessibility of accurate, inexpensive diagnostic testing, pre-natal screening and facilitating tools, missed and delayed neonatal diagnosis, restricted access, high costs, delays in obtaining medicines emergently, delayed insurance pre-approvals and high medicare copays taking considerable physician time and effort, harmful shortcuts being taken in methods to prepare medicines in settings where access is restricted, reluctance to perform ventriculoperitoneal shunts promptly when needed without recognition of potential benefit, access to resources for care, especially for marginalized populations, and limited use of recent advances in management of neurologic and retinal disease which can lead to good outcomes.