학술논문

Successful treatment of sino-pulmonary infection & skull base osteomyelitis caused by New Delhi metallo-β-lactamase-producing Pseudomonas aeruginosa in a renal transplant recipient by using an investigational antibiotic cefepime/zidebactam (WCK 5222)
Document Type
Brief Communication
Source
European Journal of Clinical Microbiology & Infectious Diseases. :1-5
Subject
New Delhi metallo-β-lactamase (NDM)
Pseudomonas aeruginosa
Cefepime/Zidebactam
Osteomyelitis
β-lactam enhancer-action
Language
English
ISSN
0934-9723
1435-4373
Abstract
A case of sino-pulmonary infection with skull base osteomyelitis due to XDR-Pseudomonas aeruginosa in renal transplant recipient was successfully treated with investigational antibiotic, cefepime/zidebactam (WCK 5222). This case highlights challenges in managing XDR-pseudomonal infection where source control was infeasible, antibiotic options were extremely limited and individualized dose adjustments were needed.