학술논문

Acute management of unstable angina and non-ST segment elevation myocardial infarction
Document Type
article
Source
einstein (São Paulo). September 2015 13(3)
Subject
Angina, unstable
Myocardial infarction
Chest pain
Myocardial ischemia/drug therapy
Language
English
ISSN
1679-4508
Abstract
Non-ST segment elevation coronary syndrome usually results from instability of an atherosclerotic plaque, with subsequent activation of platelets and several coagulation factors. Its treatment aims to reduce the ischemic pain, limiting myocardial damage and decreasing mortality. Several antiplatelet and anticoagulation agents have been proven useful, and new drugs have been added to the therapeutic armamentarium in the search for higher anti-ischemic efficacy and lower bleeding rates. Despite the advances, the mortality, infarction and readmission rates remain high.