학술논문

Nocardia veterana: disseminated infection with urinary tract infection
Document Type
report
Source
Brazilian Journal of Infectious Diseases. April 2015 19(2)
Subject
Nocardia veterana
Urinary tract infection
MALDI-TOF MS system
16S rDNA gene sequencing
Language
English
ISSN
1413-8670
Abstract
Nocardia spp. are a group of aerobic actinomycetes widely distributed in soil, and associated with severe opportunistic infections, essentially pulmonary infections. We report the first case of disseminated infection associated with urinary tract infection caused by Nocardia veterana . The diagnosis was difficult; despite the presence of pulmonary nodules, the lung biopsies remained negative while only one aerobic blood culture and the urine culture were positive for N. veterana , identified after a 16S rDNA gene sequence analysis. Few cases of clinical importance due to N. veterana have been published since its characterization. The bacteriological diagnosis of nocardiosis can be difficult to establish because of the delayed growth and the specific techniques that are required. This case illustrates the necessity of performing specific investigations in immunocompromised patients who present with infectious disease because the severity of this infection requires early diagnosis and quick initiation of appropriate antibiotic therapy.