학술논문

Original and generic preservation solutions in organ transplantation. A new paradigm?
Document Type
article
Source
Acta Cirúrgica Brasileira. January 2020 35(1)
Subject
Organ Preservation Solutions
Polyethylene Glycols
Glutathione
Calcium
Language
English
ISSN
0102-8650
Abstract
Solid organ transplantation is a very complex process, in which the storage of the graft in a preservation solution is mandatory in order to extend ischemic times and contain further damage. The condition in which the organ is transplanted is critical for the outcome of the organ recipient. The recent emergence of generic versions of organ preservation solutions (solutions with the same composition and under the same legislation as the original versions, but with different brands) compelled us to study whether the standards are maintained when comparing the original and its generic counterpart. Along these lines, we discuss and comment on some aspects concerning this issue of general interest in the organ transplantation field.