학술논문

Association between IGF-IR gene polymorphisms and productive and reproductive traits in Holstein cows
Document Type
article
Source
Arquivo Brasileiro de Medicina Veterinária e Zootecnia. December 2005 57(6)
Subject
beef cattle
reproductive efficiency
post-calving
candidate gene
Language
English
ISSN
0102-0935
Abstract
The association between single-strand conformation polymorphism (SSCP) in the gene of insulin-like growth factor-I receptor (IGF-IR) and age at first calving (AFC), calving interval (CI), lactation length (LL), and milk yield (MY) was studied using 106 graded Holstein females. The polimerase chain reaction (PCR) with specific initiating oligonucleotides, resulted an amplified fragment of 335pb. The population genotypes frequencies were 82.1% and 17.9%, for AA and AB genotypes, respectively. The frequency of A allele was 0.91 and 0.09 of B allele. No association between the identified polymorphism and AFC, CI, and MY was observed. The LL was positively associated (P<0.05) with the absence of B allele. Animals carrying the AA genotype presented a longer lactation period.