학술논문

Malaria and Vascular Endothelium
Document Type
article
Source
Arquivos Brasileiros de Cardiologia. August 2014 103(2)
Subject
Malaria
Vascular Endothelial
Communicable Disease Prognosis
Cardiovascular Diseases
Language
English
ISSN
0066-782X
Abstract
Involvement of the cardiovascular system in patients with infectious and parasitic diseases can result from both intrinsic mechanisms of the disease and drug intervention. Malaria is an example, considering that the endothelial injury by Plasmodium-infected erythrocytes can cause circulatory disorders. This is a literature review aimed at discussing the relationship between malaria and endothelial impairment, especially its effects on the cardiovascular system. We discuss the implications of endothelial aggression and the interdisciplinarity that should guide the malaria patient care, whose acute infection can contribute to precipitate or aggravate a preexisting heart disease.