학술논문
CMV and HSV-2 myeloradiculitis in an HIV infected patient
Document Type
report
Author
Source
Revista do Instituto de Medicina Tropical de São Paulo. June 2011 53(3)
Subject
Language
English
ISSN
0036-4665
Abstract
While CMV myeloradiculitis is a known complication in AIDS patients with severe immunosuppression, HSV-2 necrotizing myeloradiculitis is rare and often associated with disabling a fatal outcome. We hereby describe a 46 year-old HIV infected patient with profound and sustained immunosuppression who presented with an acute ascending paraparesis and urinary retention. Lumbar spine MRI showed contrast enhancement at the conus medullaris and cauda equine, and both CMV and HSV-2 CSF PCR were positive. Despite treatment, the patient died 20 days later. We review the main diagnostic and therapeutic aspects of herpes virus associated myeloradiculitis and discuss the approach in similar cases.