학술논문

Validity assessment of the PROMIS fatigue domain among people living with HIV
Document Type
article
Source
AIDS Research and Therapy. 14(1)
Subject
Prevention
HIV/AIDS
Infectious Diseases
Clinical Research
Good Health and Well Being
Adult
Aged
Aged
80 and over
Cross-Sectional Studies
Diagnostic Tests
Routine
Fatigue
Female
HIV Infections
Humans
Longitudinal Studies
Male
Middle Aged
Psychometrics
Young Adult
Bioengineering
HIV
PROMIS
Validity
Measurement
Patient burden
Centers for AIDS Research Network of Integrated Clinical Systems
Immunology
Virology
Language
Abstract
PurposeTo evaluate psychometric characteristics and cross-sectional and longitudinal validity of the 7-item PROMIS® Fatigue Short Form and additional fatigue items among people living with HIV (PLWH) in a nationally distributed network of clinics collecting patient reported data at the time of routine clinical care.MethodsCross-sectional and longitudinal fatigue data were collected from September 2012 through April 2013 across clinics participating in the Centers for AIDS Research Network of Integrated Clinical Systems (CNICS). We analyzed data regarding psychometric characteristics including simulated computerized adaptive testing and differential item functioning, and regarding associations with clinical characteristics.ResultsWe analyzed data from 1597 PLWH. Fatigue was common in this cohort. Scores from the PROMIS® Fatigue Short Form and from the item bank had acceptable psychometric characteristics and strong evidence for validity, but neither performed better than shorter instruments already integrated in CNICS.ConclusionsThe PROMIS® Fatigue Item Bank is a valid approach to measuring fatigue in clinical care settings among PLWH, but in our analyses did not perform better than instruments associated with less respondent burden.