학술논문

Contemporary trends and outcomes in aortic valve replacement in patients with end‐stage liver disease
Document Type
article
Source
Catheterization and Cardiovascular Interventions. 96(4)
Subject
Biomedical and Clinical Sciences
Clinical Sciences
Clinical Research
Transplantation
Cardiovascular
Patient Safety
Good Health and Well Being
Aged
Aortic Valve
Aortic Valve Stenosis
Databases
Factual
End Stage Liver Disease
Female
Heart Valve Prosthesis
Heart Valve Prosthesis Implantation
Hospital Mortality
Humans
Inpatients
Length of Stay
Male
Middle Aged
Postoperative Complications
Prosthesis Design
Recovery of Function
Retrospective Studies
Risk Assessment
Risk Factors
Severity of Illness Index
Time Factors
Transcatheter Aortic Valve Replacement
Treatment Outcome
United States
end-stage liver disease
outcomes
surgical aortic valve replacement
transcatheter aortic valve replacement
Cardiorespiratory Medicine and Haematology
Cardiovascular System & Hematology
Cardiovascular medicine and haematology
Language
Abstract
ObjectiveEven in high-risk trials pertaining to transcatheter aortic valve replacement (TAVR), patients with end-stage liver disease (ESLD) have been under-represented. We sought to study this population group from a large national United States population database.MethodsWe used National Inpatient Sample (NIS) database from January 2005 to August 2015. Patients with ESLD were extracted using Goldberg's algorithm. Propensity match analysis was done for comparative analysis between surgical aortic valve replacement (SAVR) and TAVR groups. Logistic regression analysis was used for predictors of in-hospital mortality.ResultsOut of 309,959 ESLD patients, 1,375 underwent aortic valve replacement and 1,199 patients were included in our study. Mean age was 66.1 (SD, 9.1) years. In matched data, the in-hospital mortality was 5.5% in TAVR group when compared to 19.4% in SAVR group. Ventilator use (16.1 vs. 27.2%, p