학술논문

Intersectional stigmas are associated with lower viral suppression rates and antiretroviral therapy adherence among women living with HIV
Document Type
article
Source
AIDS. 36(13)
Subject
Medical Microbiology
Biomedical and Clinical Sciences
Health Sciences
Infectious Diseases
HIV/AIDS
Prevention
Behavioral and Social Science
Infection
Anti-Retroviral Agents
Bayes Theorem
Cross-Sectional Studies
Female
HIV Infections
Humans
Medication Adherence
Social Stigma
Viral Load
antiretroviral therapy
HIV
intersectional stigmas
women with HIV
Biological Sciences
Medical and Health Sciences
Psychology and Cognitive Sciences
Virology
Biomedical and clinical sciences
Health sciences
Language
Abstract
ObjectivesTo explore the associations between intersectional poverty, HIV, sex, and racial stigma, adherence to antiretroviral therapy (ART), and viral suppression among women with HIV (WHIV).DesignWe examined intersectional stigmas, self-report ART adherence, and viral suppression using cross-sectional data.MethodsParticipants were WHIV ( N  = 459) in the Women's Adherence and Visit Engagement, a Women's Interagency HIV Study substudy. We used Multidimensional Latent Class Item Response Theory and Bayesian models to analyze intersectional stigmas and viral load adjusting for sociodemographic and clinical covariates.ResultsWe identified five intersectional stigma-based latent classes. The likelihood of viral suppression was approximately 90% lower among WHIV who experienced higher levels of poverty, sex, and racial stigma or higher levels of all intersectional stigmas compared with WHIV who reported lower experiences of intersectional stigmas. ART adherence accounted for but did not fully mediate some of the associations between latent intersectional stigma classes and viral load.ConclusionThe negative impact of intersectional stigmas on viral suppression is likely mediated, but not fully explained, by reduced ART adherence. We discuss the research and clinical implications of our findings.