학술논문
Disparities in Risks of Inadequate and Excessive Intake of Micronutrients during Pregnancy
Document Type
article
Author
Sauder, Katherine A; Harte, Robyn N; Ringham, Brandy M; Guenther, Patricia M; Bailey, Regan L; Alshawabkeh, Akram; Cordero, José F; Dunlop, Anne L; Ferranti, Erin P; Elliott, Amy J; Mitchell, Diane C; Hedderson, Monique M; Avalos, Lyndsay A; Zhu, Yeyi; Breton, Carrie V; Chatzi, Leda; Ran, Jin; Hertz-Picciotto, Irva; Karagas, Margaret R; Sayarath, Vicki; Hoover, Joseph; MacKenzie, Debra; Lyall, Kristen; Schmidt, Rebecca J; O'Connor, Thomas G; Barrett, Emily S; Switkowski, Karen M; Comstock, Sarah S; Kerver, Jean M; Trasande, Leonardo; Tylavsky, Frances A; Wright, Rosalind J; Kannan, Srimathi; Mueller, Noel T; Catellier, Diane J; Glueck, Deborah H; Dabelea, Dana; Smith, PB; Newby, KL; Benjamin, DK; Jacobson, LP; Parker, CB; Outcomes, Program Collaborators for Environmental influences on Child Health
Source
Journal of Nutrition. 151(11)
Subject
Language
Abstract
BackgroundInadequate or excessive intake of micronutrients in pregnancy has potential to negatively impact maternal/offspring health outcomes.ObjectiveThe aim was to compare risks of inadequate or excessive micronutrient intake in diverse females with singleton pregnancies by strata of maternal age, race/ethnicity, education, and prepregnancy BMI.MethodsFifteen observational cohorts in the US Environmental influences on Child Health Outcomes (ECHO) Consortium assessed participant dietary intake with 24-h dietary recalls (n = 1910) or food-frequency questionnaires (n = 7891) from 1999-2019. We compared the distributions of usual intake of 19 micronutrients from food alone (15 cohorts; n = 9801) and food plus dietary supplements (10 cohorts with supplement data; n = 7082) to estimate the proportion with usual daily intakes below their age-specific daily Estimated Average Requirement (EAR), above their Adequate Intake (AI), and above their Tolerable Upper Intake Level (UL), overall and within sociodemographic and anthropometric subgroups.ResultsRisk of inadequate intake from food alone ranged from 0% to 87%, depending on the micronutrient and assessment methodology. When dietary supplements were included, some women were below the EAR for vitamin D (20-38%), vitamin E (17-22%), and magnesium (39-41%); some women were above the AI for vitamin K (63-75%), choline (7%), and potassium (37-53%); and some were above the UL for folic acid (32-51%), iron (39-40%), and zinc (19-20%). Highest risks for inadequate intakes were observed among participants with age 14-18 y (6 nutrients), non-White race or Hispanic ethnicity (10 nutrients), less than a high school education (9 nutrients), or obesity (9 nutrients).ConclusionsImproved diet quality is needed for most pregnant females. Even with dietary supplement use, >20% of participants were at risk of inadequate intake of ≥1 micronutrients, especially in some population subgroups. Pregnancy may be a window of opportunity to address disparities in micronutrient intake that could contribute to intergenerational health inequalities.