학술논문

Global variation in anastomosis and end colostomy formation following left‐sided colorectal resection
Document Type
article
Source
BJS Open. 3(3)
Subject
Biomedical and Clinical Sciences
Clinical Sciences
Clinical Research
Colo-Rectal Cancer
Digestive Diseases
Cancer
6.4 Surgery
Evaluation of treatments and therapeutic interventions
Adult
Aged
Aged
80 and over
Anastomosis
Surgical
Colorectal Neoplasms
Colostomy
Developed Countries
Developing Countries
Elective Surgical Procedures
Emergencies
Female
Global Health
Humans
Logistic Models
Male
Middle Aged
Multivariate Analysis
Prospective Studies
GlobalSurg Collaborative
Clinical sciences
Language
Abstract
BackgroundEnd colostomy rates following colorectal resection vary across institutions in high-income settings, being influenced by patient, disease, surgeon and system factors. This study aimed to assess global variation in end colostomy rates after left-sided colorectal resection.MethodsThis study comprised an analysis of GlobalSurg-1 and -2 international, prospective, observational cohort studies (2014, 2016), including consecutive adult patients undergoing elective or emergency left-sided colorectal resection within discrete 2-week windows. Countries were grouped into high-, middle- and low-income tertiles according to the United Nations Human Development Index (HDI). Factors associated with colostomy formation versus primary anastomosis were explored using a multilevel, multivariable logistic regression model.ResultsIn total, 1635 patients from 242 hospitals in 57 countries undergoing left-sided colorectal resection were included: 113 (6·9 per cent) from low-HDI, 254 (15·5 per cent) from middle-HDI and 1268 (77·6 per cent) from high-HDI countries. There was a higher proportion of patients with perforated disease (57·5, 40·9 and 35·4 per cent; P