학술논문

EMT and Cancer: More Than Meets the Eye
Document Type
article
Source
Developmental Cell. 49(3)
Subject
Biochemistry and Cell Biology
Biological Sciences
Cancer
2.1 Biological and endogenous factors
Aetiology
Animals
Cell Differentiation
Epithelial Cells
Epithelial-Mesenchymal Transition
Humans
Neoplasms
Signal Transduction
Wound Healing
Medical and Health Sciences
Developmental Biology
Biochemistry and cell biology
Language
Abstract
Epithelial cells acquire mesenchymal characteristics during development, wound healing and inflammation, and in cancer and fibrosis. With increasing appreciation of different roles of epithelial-mesenchymal transition (EMT), we address the question of how to define and recognize EMT processes and discuss their properties in cancer progression.