학술논문
High Asymptomatic Carriage With the Omicron Variant in South Africa
Document Type
article
Author
Garrett, Nigel; Tapley, Asa; Andriesen, Jessica; Seocharan, Ishen; Fisher, Leigh H; Bunts, Lisa; Espy, Nicole; Wallis, Carole L; Randhawa, April Kaur; Miner, Maurine D; Ketter, Nzeera; Yacovone, Margaret; Goga, Ameena; Huang, Yunda; Hural, John; Kotze, Philip; Bekker, Linda Gail; Gray, Glenda E; Corey, Lawrence; Ahmed, Khatija; Badal-Faesen, Sharlaa; Barnabas, Shaun; Brumskine, William; Comline, Kim; Diacon, Andreas; Dubula, Thozama; Gill, Katherine; Grobbelaar, Coert; Innes, Craig; Kassim, Sheetal; Kotze, Sheena; Lazarus, Erica; Lombaard, Johannes; Luabeya, Angelique; Maboa, Rebone Molobane; Mahoney, Scott; Mahkaza, Disebo; Malahleha, Moelo; Malan, Daniel; Mngadi, Kathryn; Naicker, Nivashnee; Naicker, Vimla; Naidoo, Logashvari; Nchabeleng, Maphoshane; Rassool, Mohammed; Spooner, Elizabeth; Tempelman, Hugo; Mgodi, Nyaradzo; Dadabhai, Sufia; Makhema, Joe; Nuwagaba-Biribonwoha, Harriet; Samandari, Taraz; Elyanu, Peter James; Chilengi, Roma; Chirenje, Zvavahera; McElrath, Julie; Cohen, Myron; Kublin, James; Gilbert, Peter; Peda, Melissa; Andersen-Nissen, Erica; Ferrari, Guido; Villaran, Manuel; Takalani, Azwidhwi; Gildea, Marianne; Nebergall, Michelle; Sopher, Carrie; Proulx-Burns, Lori; Govender, Dhevium; Sanders, Lisa; Hanke, Jen; Baepanye, Kagisho; Le Roux, Bert; Wilvich, Haven; Sripathy, Smitha; Margineantu, Daciana; Brown, Valerie; Linton, Kim; Howell, Haley; Noronha, Bianca; Nikles, Sarah; Toledano, Alicia; May, Jeanine; El-Khorazaty, Jill; Naidoo, Keshani; Khuto, Kentse; Mayat, Fatima; Fairall, Lara; Sanne, Ian
Source
Clinical Infectious Diseases. 75(1)
Subject
Language
Abstract
We report a 23% asymptomatic severe acute respiratory syndrome coronavirus 2 (SARS CoV-2) Omicron carriage rate in participants being enrolled into a clinical trial in South Africa, 15-fold higher than in trials before Omicron. We also found lower CD4 + T-cell counts in persons with human immunodeficiency virus (HIV) strongly correlated with increased odds of being SARS-CoV-2 polymerase chain reaction (PCR) positive.