학술논문

Fetal cranial growth trajectories are associated with growth and neurodevelopment at 2 years of age: INTERBIO-21st Fetal Study
Document Type
article
Source
Nature Medicine. 27(4)
Subject
Paediatrics
Reproductive Medicine
Biomedical and Clinical Sciences
Perinatal Period - Conditions Originating in Perinatal Period
Prevention
Conditions Affecting the Embryonic and Fetal Periods
Clinical Research
Pediatric
Neurosciences
Reproductive health and childbirth
Good Health and Well Being
Cephalometry
Child Development
Female
Fetus
Humans
Infant
Infant
Newborn
Morbidity
Pregnancy
Skull
Medical and Health Sciences
Immunology
Biomedical and clinical sciences
Health sciences
Language
Abstract
Many observational studies and some randomized trials demonstrate how fetal growth can be influenced by environmental insults (for example, maternal infections)1 and preventive interventions (for example, multiple-micronutrient supplementation)2 that can have a long-lasting effect on health, growth, neurodevelopment and even educational attainment and income in adulthood3. In a cohort of pregnant women (n = 3,598), followed-up between 2012 and 2019 at six sites worldwide4, we studied the associations between ultrasound-derived fetal cranial growth trajectories, measured longitudinally from