학술논문
Ischemia With Nonobstructive Coronary Arteries: Insights From the ISCHEMIA Trial.
Document Type
article
Author
Min, James; Hague, Cameron; Berman, Daniel; Chaitman, Bernard; Picard, Michael; Hayes, Sean; Scherrer-Crosbie, Marielle; Kwong, Raymond; Lopes, Renato; Senior, Roxy; Dwivedi, Sudhanshu; Miller, Todd; Chow, Benjamin; de Silva, Ramesh; Stone, Gregg; Boden, William; Bangalore, Sripal; OBrien, Sean; Hochman, Judith; Maron, David; Reynolds, Harmony; Diaz, Ariel; Cyr, Derek; Shaw, Leslee; Mancini, G; Leipsic, Jonathon; Budoff, Matthew
Source
JACC: Cardiovascular Imaging. 16(1)
Subject
Language
Abstract
BACKGROUND: Ischemia with nonobstructive coronary arteries (INOCA) is common clinically, particularly among women, but its prevalence among patients with at least moderate ischemia and the relationship between ischemia severity and non-obstructive atherosclerosis severity are unknown. OBJECTIVES: The authors investigated predictors of INOCA in enrolled, nonrandomized participants in ISCHEMIA (International Study of Comparative Health Effectiveness with Medical and Invasive Approaches), sex differences, and the relationship between ischemia and atherosclerosis in patients with INOCA. METHODS: Core laboratories independently reviewed screening noninvasive stress test results (nuclear imaging, echocardiography, magnetic resonance imaging or nonimaging exercise tolerance testing), and coronary computed tomography angiography (CCTA), blinded to results of the screening test. INOCA was defined as all stenoses