학술논문

Cardiovascular Biomarkers and Imaging in Older Adults JACC Council Perspectives
Document Type
article
Source
Journal of the American College of Cardiology. 76(13)
Subject
Biomedical and Clinical Sciences
Clinical Sciences
Aging
Cardiovascular
Heart Disease
4.1 Discovery and preclinical testing of markers and technologies
Detection
screening and diagnosis
4.2 Evaluation of markers and technologies
Good Health and Well Being
Aged
Biomarkers
Cardiac Imaging Techniques
Exercise Test
Humans
aging
biomarkers
cardiovascular testing
imaging
shared decision making
stress testing
Geriatric Cardiology Section Leadership Council
Cardiorespiratory Medicine and Haematology
Public Health and Health Services
Cardiovascular System & Hematology
Cardiovascular medicine and haematology
Language
Abstract
Whereas the burgeoning population of older adults is intrinsically vulnerable to cardiovascular disease, the utility of many management precepts that were validated in younger adults is often unclear. Whereas biomarker- and imaging-based tests are a major part of cardiovascular disease care, basic assumptions about their use and efficacy cannot be simply extrapolated to many older adults. Biology, physiology, and body composition change with aging, with important influences on cardiovascular disease testing procedures and their interpretation. Furthermore, clinical priorities of older adults are more heterogeneous, potentially undercutting the utility of testing data that are collected. The American College of Cardiology and the National Institutes on Aging, in collaboration with the American Geriatrics Society, convened, at the American College of Cardiology Heart House, a 2-day multidisciplinary workshop, "Diagnostic Testing in Older Adults with Cardiovascular Disease," to address these issues. This review summarizes key concepts, clinical limitations, and important opportunities for research.