학술논문

Long-term kidney function, proteinuria, and associated risks among HIV-infected and uninfected men
Document Type
article
Source
AIDS. 32(10)
Subject
Cardiovascular
Infectious Diseases
Kidney Disease
Clinical Research
HIV/AIDS
6.1 Pharmaceuticals
Evaluation of treatments and therapeutic interventions
Renal and urogenital
Infection
Good Health and Well Being
Adult
Aged
Anti-Retroviral Agents
Antiretroviral Therapy
Highly Active
Glomerular Filtration Rate
HIV Infections
Humans
Longitudinal Studies
Male
Middle Aged
Prevalence
Prospective Studies
Proteinuria
Risk Factors
Young Adult
HIV serostatus differences
longitudinal glomerular filtration rate
proteinuria
risks
Biological Sciences
Medical and Health Sciences
Psychology and Cognitive Sciences
Virology
Language
Abstract
BackgroundFactors affecting kidney function and proteinuria among HIV-positive (HIV+) and HIV-negative (HIV-) persons need better characterization.MethodsWe evaluated estimated glomerular filtration rate (eGFR, ml/min per 1.73 m) changes, proteinuria prevalence (a urine protein-to-creatinine ratio of ≥0.2 at two consecutive visits) and associated factors among HIV+ and HIV- men.ResultsThere were 917 HIV+ men receiving HAART, 159 HIV+ men not receiving HAART, and 1305 HIV- men seen from October 2003 to September 2014. Median annual eGFR change was -0.5, -0.8% for HIV+ and -0.3% for HIV- men (P