학술논문

The human body at cellular resolution: the NIH Human Biomolecular Atlas Program
Document Type
article
Author
Snyder, Michael PLin, ShinPosgai, AmandaAtkinson, MarkRegev, AvivRood, JenniferRozenblatt-Rosen, OritGaffney, LeslieHupalowska, AnnaSatija, RahulGehlenborg, NilsShendure, JayLaskin, JuliaHarbury, PehrNystrom, Nicholas ASilverstein, Jonathan CBar-Joseph, ZivZhang, KunBörner, KatyLin, YiingConroy, RichardProcaccini, DenaRoy, Ananda LPillai, AjayBrown, MarishkaGalis, Zorina SCai, LongTrapnell, ColeJackson, DanaNolan, GarryGreenleaf, William JamesPlevritis, SylviaAhadi, SaraNevins, Stephanie ALee, HayanSchuerch, Christian MartijnBlack, SarahVenkataraaman, Vishal GauthamEsplin, EdHorning, AaronBahmani, AmirSun, XinJain, SanjayHagood, JamesPryhuber, GloriaKharchenko, PeterBodenmiller, BerndBrusko, ToddClare-Salzler, MichaelNick, HarryOtto, KevinWasserfall, CliveJorgensen, MardaBrusko, MaiganMaffioletti, SergioCaprioli, Richard MSpraggins, Jeffrey MGutierrez, DaniellePatterson, Nathan HeathNeumann, Elizabeth KHarris, RaymonddeCaestecker, MarkFogo, Agnes Bvan de Plas, RafLau, KenYuan, Guo-ChengZhu, QianDries, RubenYin, PengSaka, Sinem KKishi, Jocelyn YWang, YuGoldaracena, IsabelYe, DongHyeBurnum-Johnson, Kristin EPiehowski, Paul DAnsong, CharlesZhu, YingDesai, TusharMulye, JayChou, PeterNagendran, MonicaTeichmann, Sarah APaten, BenedictMurphy, Robert FMa, JianKiselev, Vladimir YuKingsford, CarlRicarte, Allyson
Source
Nature. 574(7777)
Subject
Human Genome
Genetics
Networking and Information Technology R&D
Bioengineering
Aging
Atlases as Topic
Biomedical Research
Female
Health
Humans
International Cooperation
Male
Models
Anatomic
Molecular Biology
National Institutes of Health (U.S.)
Organ Specificity
Single-Cell Analysis
United States
q-bio.OT
General Science & Technology
Language
Abstract
Transformative technologies are enabling the construction of threedimensional (3D) maps of tissues with unprecedented spatial and molecularresolution. Over the next seven years, the NIH Common Fund Human BiomolecularAtlas Program (HuBMAP) intends to develop a widely accessible framework forcomprehensively mapping the human body at single-cell resolution by supportingtechnology development, data acquisition, and detailed spatial mapping. HuBMAPwill integrate its efforts with other funding agencies, programs, consortia,and the biomedical research community at large towards the shared vision of acomprehensive, accessible 3D molecular and cellular atlas of the human body, inhealth and various disease settings.