부산대학교 도서관

INTRODUCTION:: Choroidal hemangiomas are present in 20% to 70% of patients with Sturge–Weber syndrome (SWS) and may lead to exudative retinal detachment. The treatment includes retinal photocoagulation, photodynamic therapy, and cryocoagulation, however they are frequently ineffective. We report a case of exudative retinal detachment secondary to SWS that appears to have improved with oral acetazolamide. PATIENT CONCERNS:: A 22-year-old man was diagnosed with congenital SWS due to a hemangioma in the first and second branches of the right trigeminal nerve. In April 2009, the patient was referred to the Ophthalmological department with reduced vision. The best-corrected visual acuity (decimal) of the right eye was reduced while its intraocular pressure was increased. The right anterior chamber depth was shallow, and exudative retinal detachment associated with choroidal hemangioma in the right eye was observed. Fluorescein angiography showed fluorescence leakage from a choroidal hemangioma. DIAGNOSIS:: We diagnosed exudative retinal detachment secondary to SWS. INTERVENTIONS:: Acetazolamide was taken orally at 500 mg daily for 2 weeks. OUTCOMES:: Following the 2-week acetazolamide treatment, both the laterality of the anterior chamber depth and the exudative retinal detachment resolved and the best-corrected visual acuity and intraocular pressure improved. There was no fluorescence leakage from hemangioma observed on fluorescein angiography. In July 2013, a blunt trauma to the right eye caused a relapse of the exudative retinal detachment in this eye. Similarly, oral acetazolamide treatment for 2 weeks relieved exudative retinal detachment, and no subsequent relapse was observed. CONCLUSIONS:: Oral acetazolamide appeared to be effective for exudative retinal detachment associated with choroidal hemangiomas in a patient with SWS.