학술논문
Efficacy of short-term adjunctive subantimicrobial dose doxycycline in diabetic patients – randomized study
Document Type
Academic Journal
Source
Oral Diseases. Nov 01, 2012 18(8):763-770
Subject
Language
English
ISSN
1354-523X
Abstract
OBJECTIVE:: METHODS:: RESULTS:: Clinical attachment level, PD, and BOP improved significantly in both groups after therapy ( P < 0.05). The statistically significant difference between the two groups after the therapy was observed only in PD in tooth sites with initial PD ≥ 4 mm (SRP + placebo: 3.41 ± 0.6 mm vs SRP + SDD: 2.92 ± 0.5 mm, P < 0.05). GCF matrix metalloproteinase-8 levels were significantly reduced only in SRP + SDD group ( P < 0.01). There were no changes in HbA1c levels after therapy. CONCLUSION:: Oral Diseases (2012) 18, 763–770