학술논문
Burden of Stroke in Europe: An Analysis of the Global Burden of Disease Study Findings From 2010 to 2019
Document Type
Academic Journal
Author
Prendes, Carlota F.; Rantner, Barbara; Hamwi, Tarek; Stana, Jan; Feigin, Valery L.; Stavroulakis, Konstantinos; Tsilimparis, Nikolaos; Fernandez Prendes, Carlota; Rantner, Barbara; Hamwi, Tarek; Stana, Jan; Feigin, Prof Valery L; Stavroulakis, Konstantinos; Tsilimparis, Nikolaos; Aboyans, Prof Victor; Olusola Akinyemi, Rufus; Al-Shahi Salman, Prof Rustam; Artamonov, Anton A; Aujayeb, Avinash; Baldereschi, Marzia; Basu, Sanjay; Béjot, Prof Yannick; Belo, Luis; Bennett, Derrick A; Srikanth Bhagavathula, Akshaya; Bikbov, Boris; Brenner, Prof Hermann; Luciano Caetano dos Santos, Florentino; Carrero, Prof Juan J; Carvalho, Prof Felix; Catapano, Prof Alberico L; Charalampous, Periklis; Christensen, Prof Hanne; Chung, Sheng-Chia; Angelo Cortesi, Paolo; Marisa Costa, Vera; Cyganska, Malgorzata; D’Amico, Emanuele; Davletov, Kairat; Georgieva Dokova, Klara; Douiri, Abdel; Francis Fagbamigbe, Adeniyi; Fischer, Florian; Ghith, Nermin; Giampaoli, Simona; Singh Gill, Prof Paramjit; Gnedovskaya, Elena V; Havmoeller, Rasmus J; Hostiuc, Sorin; Iavicoli, Prof Ivo; Ilic, Prof Milena D; Isola, Prof Gaetano; Jerzy Jozwiak, Jacek; Jürisson, Mikk; Kayode, Gbenga A; Khan, Moien AB; Khatab, Prof Khaled; Kisa, Prof Adnan; Kivimäki, Prof Mika; Koyanagi, Ai; Kulimbet, Mukhtar; Kusuma, Dian; La Vecchia, Prof Carlo; Lacey, Ben; Lallukka, Prof Tea; Lorkowski, Prof Stefan; Majeed, Prof Azeem; Giovanni Mantovani, Prof Lorenzo; Mazzaglia, Giampiero; Mentis, Alexios-Fotios A; Meretoja, Atte; Miao Jonasson, Junmei; Mirica, Andreea; Mirrakhimov, Prof Erkin M; Mohammed, Shafiu; Molokhia, Mariam; Monasta, Lorenzo; Mons, Prof Ute; Morze, Jakub; Irina Negoi, Ruxandra; Norrving, Prof Bo; Oancea, Prof Bogdan; O’Caoimh, Rónán; Orru, Hans; Padron-Monedero, Alicia; Pedersini, Paolo; Perico, Norberto; Polibin, Roman V; Polinder, Suzanne; Raggi, Alberto; Rawaf, Prof Salman; Remuzzi, Prof Giuseppe; Romoli, Michele; Sacco, Prof Simona; Reza Saeb, Prof Mohammad; Vasco Santos, João; Santric-Milicevic, Prof Milena M; Aleksandrovna Skryabina, Anna; Smith, Lee; Starodubova, Antonina V; Stevanović, Aleksandar; Stranges, Prof Saverio; Teuschl, Yvonne; Topor-Madry, Roman; Touvier, Mathilde; Tovani-Palone, Marcos Roberto; Unim, Brigid; Juhani Vasankari, Prof Tommi; Volovici, Victor; Wafa, Hatem A; Wang, Yanzhong; Westerman, Ronny; Wolfe, Prof Charles D A; Yesiltepe, Metin; Zanghì, Aurora; Sergeevich Zastrozhin, Prof Mikhail
Source
Stroke. Feb 01, 2024 55(2):432-442
Subject
Language
English
ISSN
0039-2499
Abstract
BACKGROUND:: While most European Regions perform well in global comparisons, large discrepancies within stroke epidemiological parameters exist across Europe. The objective of this analysis was to evaluate the stroke burden across European regions and countries in 2019 and its difference to 2010. METHODS:: The GBD 2019 analytical tools were used to evaluate regional and country-specific estimates of incidence, prevalence, deaths, and disability-adjusted life years of stroke for the European Region as defined by the World Health Organization, with its 53 member countries (EU-53) and for European Union as defined in 2019, with its 28 member countries (EU-28), between 2010 and 2019. Results were analyzed at a regional, subregional, and country level. RESULTS:: In EU-53, the absolute number of incident and prevalent strokes increased by 2% (uncertainty interval [UI], 0%–4%), from 1 767 280 to 1 802 559 new cases, and by 4% (UI, 3%–5%) between 2010 and 2019, respectively. In EU-28, the absolute number of prevalent strokes and stroke-related deaths increased by 4% (UI, 2%–5%) and by 6% (UI, 1%–10%), respectively. All-stroke age-standardized mortality rates, however, decreased by 18% (UI, −22% to −14%), from 82 to 67 per 100 000 people in the EU-53, and by 15% (UI, −18% to −11%), from 49.3 to 42.0 per 100 000 people in EU-28. Despite most countries presenting reductions in age-adjusted incidence, prevalence, mortality, and disability-adjusted life year rates, these rates remained 1.4×, 1.2×, 1.6×, and 1.7× higher in EU-53 in comparison to the EU-28. CONCLUSIONS:: EU-53 showed a 2% increase in incident strokes, while they remained stable in EU-28. Age-standardized rates were consistently lower for all-stroke burden parameters in EU-28 in comparison to EU-53, and huge discrepancies in incidence, prevalence, mortality, and disability-adjusted life-year rates were observed between individual countries.