학술논문
Selective renal blood perfusion induces renal tubules injury in a porcine model
Document Type
Academic Journal
Author
Source
Journal of Vascular Surgery. Mar 01, 2016 63(3):778-787
Subject
Language
English
ISSN
0741-5214
Abstract
OBJECTIVE:: METHODS:: RESULTS:: With normal mean arterial blood pressures, flow rates in the renal arteries during perfusion decreased to 75% (group II) with DAP and to 50% (group III) with SRP compared with the control animals (group I; P = .0279 for I vs II; P = .0002 for I vs III). Microcirculation, measured by microspheres, did not differ significantly among the groups. In contrast, O2ER (P = .0021 for I vs III) and neutrophil gelatinase-associated lipocalin (P = .0083 for I vs III) levels were significantly increased in group III, whereas free hemoglobin was increased in groups II and III (P = .0406 for I vs II; P = .0018 for I vs III). CONCLUSIONS:: CLINICAL RELEVANCE