학술논문
The Atrial Fibrillation Ablation Pilot Study: an European Survey on Methodology and results of catheter ablation for atrial fibrillation conducted by the European Heart Rhythm Association
Document Type
Academic Journal
Author
Arbelo, Elena; Brugada, Josep; Hindricks, Gerhard; Maggioni, Aldo P.; Tavazzi, Luigi; Vardas, Panos; Laroche, Cécile; Anselme, Frédéric; Inama, Giuseppe; Jais, Pierre; Kalarus, Zbigniew; Kautzner, Josef; Lewalter, Thorsten; Mairesse, Georges H.; Perez-Villacastin, Julian; Riahi, Sam; Taborsky, Milos; Theodorakis, George; Trines, Serge A.; Brugada, Josep; Arbelo, Elena; Hindriks, Gerhard; Maggioni, Aldo P.; Morgan, John; Tavazzi, Luigi; Vardas, Panos; Alonso, Angeles; Ferrari, Roberto; Komajda, Michel; Tavazzi, Luigi; Wood, David; Vardas, Panos; Brugada, Josep; Mairesse, Georges; Taborsky, Milos; Kautzner, Josef; Lewalter, Thorsten; Riahi, Sam; Jais, Pierre; Anselme, Frédéric; Theodorakis, George; Inama, Giuseppe; Trines, Serge; Kalarus, Zbigniew; Villacastin, Julian Perez; Maggioni, Aldo P.; Manini, Malika; Gracia, Gérard; Laroche, Cécile; Missiamenou, Viviane; Taylor, Charles; Konte, Marème; Fiorucci, Emanuela; Lefrancq, Elin Folkesson; Glémot, Myriam; McNeill, Patti-Ann; Bois, Timothée; Heidbüchel, H.; Nuyens, D.; Boland, J.; Dinraths, V.; Herzet, J.-M.; Hoffer, E.; Malmendier, D.; Massoz, M.; Pourbaix, S.; Ballant, E.; Blommaert, D.; Deceuninck, O.; Dormal, F.; Xhaet, O.; De Potter, T.; Geelen, P.; Derycker, K.; Duytschaever, M.; Tavernier, R.; Vandekerckhove, Y.; Vankats, D.; Bulava, A.; Hanis, J.; Sitek, D.; Blahova, M.; Cihak, R.; Hanyasova, L.; Jansova, H.; Peichl, P.; Tanzerova, M.; Wichterle, D.; Duda, J.; Haman, L.; Parizek, P.; Coling, L.; Neuzil, P.; Petru, J.; Sediva, L.; Skoda, J.; Chovancik, J.; Fiala, M.; Neuwirth, R.; Karlsdottir, A.; Pehrson, S.; Gerdes, C.; Jensen, H.K.; Lukac, P.; Nielsen, J. C.; Hansen, J.; Johannessen, A.; Hansen, P. S.; Pedersen, A.K.; Heath, F.P.; Hjortshoj, S.; Thogersen, A.M.; Da Costa, A.; Martel, I.; Romeyer-Bouchard, C.; Sadki, N.; Schmid, A.; Haissaguerre, M.; Hocini, M.; Knecht, S.; Sacher, F.; Ait Said, M.; Cauchemez, B.; Ledoux, F.; Thomas, O.; Cebron, J.-P.; Decarsin, N.; Gras, D.; Hervouet, S.; Durand, C.; Durand-Dubief, A.; Poty, H.; Babuty, D.; Pierre, B.; Albenque, J.-P.; Boveda, S.; Combes, N.; Mas, R.; Hermida, J-S.; Kubala, M.; Godin, B.; Savouré, A.; Soublin, Y.; Defaye, P.; Jacon, P.; Brigadeau, F.; Corbut, S.; Flament-Balzola, F.; Kacet, S.; Klug, D.; Lacroix, D.; Copie, X.; Gilles, L.; Hocine, Z.; Paziaud, O.; Piot, O.; Crocq, C.; Kaballu, G.; Le Moal, V.; Lotton, P.; Mabo, P.; Pavin, D.; Andronache, M.; De Chillou, C.; Magnin-Poull, I.; Deharo, J.-C.; Durand, C.; Franceschi, F.; Peyrouse, E.; Prevot, S.; Etchegoin, M.; Extramiana, F.; Leenhardt, A.; Messali, A.; Heine, T.; Schneider, A.; Winter, N.; Brachmann, J.; Ritscher, G.; Schertel-Gruenler, B.; Simon, H.; Sinha, A.-M.; Turschner, O.; Wystrach, A.; Stemberg, M.; Kuck, K.-H.; Metzner, A.; Tilz, R.; Wissner, E.; Heitmann, K.; Willems, S.; Andresen, D.; Mueller, S.; Volkmer, M.; Schmidt, B.; Kostopoulou, A.; Livanis, E.; Voudris, V.; Efremidis, M.; Letsas, K.; Tsikrikas, S.; Christoforatou, E.; Ioannidis, P.; Katsivas, A.; Kourouklis, S.; Andrikopoulos, G.; Rassias, I.; Tzeis, S.; Dakos, G.; Paraskevaidis, S.; Stavropoulos, G.; Theofilogiannakos, E.; Vassilikos, V.P.; Bongiorni, M.G.; Zucchelli, G.; Raviele, A.; Themistoclakis, S.; Pratola, C.; Tritto, M.; Della Bella, P.; Mazzone, P.; Moltrasio, M.; Tondo, C.; Calo, L.; De Luca, L.; Guarracini, F.; Lioy, E.; Dozza, L.; Frigoli, E.; Giannelli, L.; Pappone, C.; Saviano, M.; Schiavina, G.; Vicedomini, G.G.; De Ponti, R.; Doni, L. A.; Marazzi, R.; Salerno-Uriarte, J.A.; Tamborini, C.; Anselmino, M.; Ferraris, F.; Gaita, F.; Bertaglia, E.; Brandolino, G.; Zoppo, F.; De Groot, N.; Janse, P.; Jordaens, L.; Pison, L.; Roos, C.; Van Gelder, I.; Manusama, R.; Meijer, A.; Van der Voort, P.; Trines, S.; Compier, Marieke G.; Kazmierczak, J.; Kornacewicz-Jach, Z.; Wielusinski, M.; Baran, J.; Kulakowski, P.; Dzidowski, M.; Fuglewicz, A.; Nowak, K.; Pruszkowska-Skrzep, P.; Wozniak, A.; Nowak, S.; Trusz-Gluza, M.; Almendral, J.; Atienza, F.; Castellanos, E.; De Diego, C.; Ortiz, M.; Moreno Planas, J.; Perez Castellano, N.; Benezet, J.; Farre Muncharaz, J.; Rubio Campal, J.M.; Hernandez Madrid, A.; Matia, R.; Arana, E.; Pedrote, A.; Cozar, R.; Peinado, R.; Valverde, I.; Arbelo, E.; Berruezo, A.; Calvo, N.; Guiu, E.; Husseini, S.; Mont Girbau, L.
Source
European Heart Journal. Jun 07, 2014 35(22):1466-1478
Subject
Language
English
ISSN
0195-668X
Abstract
AIMS: The Atrial Fibrillation Ablation Pilot Study is a prospective registry designed to describe the clinical epidemiology of patients undergoing an atrial fibrillation (AFib) ablation, and the diagnostic/therapeutic processes applied across Europe. The aims of the 1-year follow-up were to analyse how centres assess in routine clinical practice the success of the procedure and to evaluate the success rate and long-term safety/complications. METHODS AND RESULTS: Seventy-two centres in 10 European countries were asked to enrol 20 consecutive patients undergoing a first AFib ablation procedure. A web-based case report form captured information on pre-procedural, procedural, and 1-year follow-up data. Between October 2010 and May 2011, 1410 patients were included and 1391 underwent an AFib ablation (98.7%). A total of 1300 patients (93.5%) completed a follow-up control 367 ± 42 days after the procedure. Arrhythmia documentation was done by an electrocardiogram in 76%, Holter-monitoring in 52%, transtelephonic monitoring in 8%, and/or implanted systems in 4.5%. Over 50% became asymptomatic. Twenty-one per cent were re-admitted due to post-ablation arrhythmias. Success without antiarrhythmic drugs was achieved in 40.7% of patients (43.7% in paroxysmal AF; 30.2% in persistent AF; 36.7% in long-lasting persistent AF). A second ablation was required in 18% of the cases and 43.4% were under antiarrhythmic treatment. Thirty-three patients (2.5%) suffered an adverse event, 272 (21%) experienced a left atrial tachycardia, and 4 patients died (1 haemorrhagic stroke, 1 ventricular fibrillation in a patient with ischaemic heart disease, 1 cancer, and 1 of unknown cause). CONCLUSION: The AFib Ablation Pilot Study provided crucial information on the epidemiology, management, and outcomes of catheter ablation of AFib in a real-world setting. The methods used to assess the success of the procedure appeared at least suboptimal. Even in this context, the 12-month success rate appears to be somewhat lower to the one reported clinical trials.