학술논문
Clinical and Optical Coherence Tomography Correlation of Recurrence Patterns After Femtosecond Laser–Assisted Anterior Lamellar Keratoplasty in Reis–Bucklers Corneal Dystrophy
Document Type
Academic Journal
Author
Source
Cornea. Apr 01, 2024 43(4):459-465
Subject
Language
English
ISSN
0277-3740
Abstract
PURPOSE:: The aim of this study was to report the clinical profile and patterns of recurrence after femtosecond laser–assisted anterior lamellar keratoplasty (FALK) in Reis–Bucklers corneal dystrophy. METHODS:: This is a case series of 5 eyes of 4 patients with Reis–Bucklers corneal dystrophy. Clinical images of recurrence were correlated with the high-resolution optical coherence tomography. Histopathologic examination of excised corneal samples was performed when possible. RESULTS:: The median time to recurrence was 2 (1–5) years after FALK. Of the 5 eyes, 1 eye had primary FALK, whereas 4 eyes had secondary interventions, which included previous phototherapeutic keratectomy (once in 1 eye and twice in 2 eyes), and previous penetrating keratoplasty, followed by phototherapeutic keratectomy (1 eye). Recurrence was noted at the level of the subepithelium. In addition, 1 eye showed interface deposits along with epithelial downgrowth at the graft–host bed. CONCLUSIONS:: The 2 distinct patterns of recurrence noted were at the subepithelial region and the interface. The clinical patterns of recurrence favor an epithelial origin of recurrent deposits.