학술논문
Levamisole and Chronic Delta Hepatitis
Document Type
Academic Journal
Source
Annals of Internal Medicine. Jun 01, 1983 98(6):1024-1024
Subject
Language
English
ISSN
0003-4819
Abstract
To the editor: A cause of liver damage in carriers of hepatitis B surface antigen (HBsAg) is the newly described hepatitis B virus-associated delta agent (1); delta hepatitis may be a progressive disease, unresponsive to steroids and immunosuppressors (2). We studied whether levamisole, a drug restoring peripheral lymphocyte function in patients with impaired cellular immunity (3), may be beneficial in patients with chronic delta hepatitis.A pilot study was done in 16 carriers of hepatitis B virus with chronic active hepatitis, 8 with intrahepatic hepatitis B core antigen, (HBcAg) and 8 with delta antigen detected by immunofluorescence. Ten patients were