학술논문
A Rare Case of Undifferentiated Carcinoma of the Colon Directly Invading the Duodenum
Document Type
Article
Source
(2023): 49-54.
Subject
Language
Korean
ISSN
29509394
Abstract
Colorectal cancers often invade adjacent organs; however, direct duodenal invasion is rare. Adenocarcinoma is the most common type of colorectal cancer, but an undifferentiated carcinomatype is unusual. Herein, we present a case of undifferentiated carcinoma of the colon that directly invaded the duodenum and metastasized to distant lymph nodes. An 85-year-old femalepatient was admitted with a 7-cm-sized colonic mass invading the duodenum, detected by computed tomography. Positron emission tomography revealed fluorodeoxyglucose uptake in thecolon, duodenum, and aortocaval lymph nodes. A large encircling mass in the ascending colonand an ulcerated mass in the duodenum were revealed by colonoscopy and esophagogastroduodenoscopy, respectively. Pathologic examinations of the colon and the duodenum revealednonglandular, diffusely infiltrating atypical round cells, confirming undifferentiated carcinomaof the colon. The histologic type of this tumor was distinguished using immunohistochemical(IHC) markers. Finally, microscopic characteristics and IHC markers aided in identifying thehistologic type of colorectal cancer.
Colorectal cancers often invade adjacent organs; however, direct duodenal invasion is rare. Adenocarcinoma is the most common type of colorectal cancer, but an undifferentiated carcinomatype is unusual. Herein, we present a case of undifferentiated carcinoma of the colon that directly invaded the duodenum and metastasized to distant lymph nodes. An 85-year-old femalepatient was admitted with a 7-cm-sized colonic mass invading the duodenum, detected by computed tomography. Positron emission tomography revealed fluorodeoxyglucose uptake in thecolon, duodenum, and aortocaval lymph nodes. A large encircling mass in the ascending colonand an ulcerated mass in the duodenum were revealed by colonoscopy and esophagogastroduodenoscopy, respectively. Pathologic examinations of the colon and the duodenum revealednonglandular, diffusely infiltrating atypical round cells, confirming undifferentiated carcinomaof the colon. The histologic type of this tumor was distinguished using immunohistochemical(IHC) markers. Finally, microscopic characteristics and IHC markers aided in identifying thehistologic type of colorectal cancer.
Colorectal cancers often invade adjacent organs; however, direct duodenal invasion is rare. Adenocarcinoma is the most common type of colorectal cancer, but an undifferentiated carcinomatype is unusual. Herein, we present a case of undifferentiated carcinoma of the colon that directly invaded the duodenum and metastasized to distant lymph nodes. An 85-year-old femalepatient was admitted with a 7-cm-sized colonic mass invading the duodenum, detected by computed tomography. Positron emission tomography revealed fluorodeoxyglucose uptake in thecolon, duodenum, and aortocaval lymph nodes. A large encircling mass in the ascending colonand an ulcerated mass in the duodenum were revealed by colonoscopy and esophagogastroduodenoscopy, respectively. Pathologic examinations of the colon and the duodenum revealednonglandular, diffusely infiltrating atypical round cells, confirming undifferentiated carcinomaof the colon. The histologic type of this tumor was distinguished using immunohistochemical(IHC) markers. Finally, microscopic characteristics and IHC markers aided in identifying thehistologic type of colorectal cancer.