부산대학교 도서관

Purpose: The study aim was to investigate factors influencing the quality of life of patients with pancreatobiliary cancer who were receiving chemotherapy. Methods: In this cross-sectional correlational study, participants were 130 patients diagnosed with pancreatobiliary cancer who were receiving chemotherapy at a university-affiliated hospital in South Korea. The data were collected between June 2022 and January 2023. Physical symptoms, perceived health status, anxiety, depression, social support, and quality of life were assessed. Data were analyzed by a hierarchical multiple regression analysis using SPSS 25.0 software. Results: The mean age was 65.15 years, with men comprising 50.8% of the study sample, and the mean disease duration was 5.29 months. Results of the hierarchical regression analysis identified factors influencing the quality of life of the participants: physical symptoms (β=-.35, p<.001), anxiety (β=-.30, p<.001), depression (β=-.19, p=.003), social support (β=.18, p<.001), and perceived health status (β=.13, p=.010). The explanatory power of the final model was 81.0% (F=50.73, p<.001). Conclusion: The holistic and multifaceted efforts of healthcare professionals are recommended to improve the quality of life of patients with pancreatobiliary cancer. Specifically, necessary actions to improve the quality of life of the patients include closely identifying patients’ physical symptoms and perceived health status, assessing and providing early interventions for anxiety and depression, and ensuring social support, including support from family caregivers and healthcare professionals.