학술논문
Cigarette Smoking, Smoking Cessation, and Bladder Cancer Risk: A Pooled Analysis of 10 Cohort Studies in Japan
Document Type
Journal Article
Author
Akiko Tamakoshi; Chisato Nagata; Hidemi Ito; Hiroyuki Masaoka; Ichiro Tsuji; Isao Oze; Keiko Wada; Keitaro Matsuo; Keitaro Tanaka; Kotaro Ozasa; Ling Zha; Manami Inoue; Norie Sawada; Ritsu Sakata; Sarah Krull Abe; Shoichiro Tsugane; Takashi Kimura; Tetsuhisa Kitamura; Tetsuya Mizoue; Yingsong Lin; Yumi Sugawara
Source
Journal of Epidemiology. 2023, 33(11):582
Subject
Language
English
ISSN
0917-5040
1349-9092
1349-9092
Abstract
Results: During 4,729,073 person-years of follow-up, 936 men and 325 women developed bladder cancer. In men, former smokers (HR 1.47; 95% CI, 1.18–1.82) and current smokers (HR 1.96; 95% CI, 1.62–2.38) had higher risk than never smokers. In women, current smokers had higher risk than never smokers (HR 2.35; 95% CI, 1.67–3.32). HRs in men linearly increased with increasing pack-years. Risk decreased with increasing years of smoking cessation in men, with a significant dose-response trend. Former smokers with a duration of more than 10 years after smoking cessation had no significantly increased risk compared with never smokers (HR 1.26; 95% CI, 0.97–1.63).