학술논문

Cerebrovascular Events After Myocardial Infarction: Analysis Of The GISSI Trial
Document Type
research-article
Source
BMJ: British Medical Journal, 1991 Jun . 302(6790), 1428-1431.
Subject
Myocardial infarction
Strokes
Control groups
Predisposing factors
Fibrinolytics
Mortality
Confidence interval
Thrombosis
Experimentation
Echocardiography
Language
English
ISSN
09598138
17561833
Abstract
Objectives—To describe the epidemiology of cerebrovascular events in patients given or not given fibrinolytic treatment and to assess the prognostic implications and risk factors. Design—Case series derived from the GISSI randomised trial. Setting—176 coronary care units in Italy giving various levels of care. Patients—5860 patients with acute myocardial infarction treated with 1.5 million units of intravenous streptokinase and 5852 patients not given fibrinolytic treatment. Main outcome measures—Cerebrovascular event, sex, age, blood pressure, history of previous infarct, site of infarction, and Killip class. Results—99 of 11 712 patients (0.84%) had a cerebrovascular event. Older age, worse Killip class, and anterior location of infarction seemed to be risk factors for cerebrovascular events (40/3201 aged 65-75 v 42/7295 aged