부산대학교 도서관

Background Depression and anxiety are commonly observed in people with multiple sclerosis (pwMS). There is a growing body of literature supporting the hypothesis that personality traits can influence the mood disorders. This study aimed to investigate the personality traits and their relationships with depression and anxiety among pwMS. Methods 234 pwMS were involved in this cross-sectional study. Personality traits, depression, and anxiety were assessed using the NEO Five-Factor Inventory (NEO-FFI) and Hospital Anxiety and Depression Scale (HADS), respectively. Pearson's correlation coefficient and generalized linear model were employed to evaluate the relationships between demographic and clinical characteristics, NEO-FFI, and HADS subscales. Results In pwMS, longer disease duration was significantly associated with lower level of conscientiousness ([beta] = - 0.23, p = 0.008) and agreeableness ([beta] = - 0.2, p = 0.01). Moreover, higher expanded disability status scale (EDSS) of pwMS had a significant relationship with higher level of neuroticism ([beta] = 0.89, p = 0.01). Increased level of neuroticism was significantly correlated with lower level of extraversion (r = - 0.28, p < 0.001), openness (r = - 0.37, p < 0.001), agreeableness (r = - 0.31, p < 0.001), and conscientiousness (r = - 0.45, p < 0.001). PwMS with higher level of conscientiousness showed more extraversion (r = 0.23, p < 0.001), openness (r = 0.61, p < 0.001), and agreeableness (r = 0.41, p < 0.001). Elevated level of neuroticism was significantly associated with higher level of anxiety ([beta] = 0.47, p < 0.001) and depression ([beta] = 0.11, p < 0.001) among pwMS. Conclusion The co-occurrence of depression and anxiety is probably associated with neuroticism among pwMS. Additionally, the impact of personality traits extends to influencing key disease aspects such as physical disability and disease duration in MS. Keywords: Personality traits, Depression, Anxiety, Multiple Sclerosis
Author(s): Saeed Vaheb[sup.1], Yousef Mokary[sup.2], Mohammad Yazdan Panah[sup.2], Aysa Shaygannejad[sup.1], Alireza Afshari-Safavi[sup.3], Majid Ghasemi[sup.1,4], Vahid Shaygannejad[sup.1,4], Elham Moases Ghaffary[sup.1] and Omid Mirmosayyeb[sup.1] Introduction Multiple sclerosis (MS) is an autoimmune disease [...]