부산대학교 도서관

Introduction: Medical cannabis may provide a treatment option for chronic neuropathic pain. However, empirical disease-specific data are scarce. Methods: This is a retrospective observational study including 99 patients with chronic neuropathic pain. These patients received medical cannabis by means of inhaling dried flowers with tetrahydrocannabinol content of 6) decreased from 96% to 16% (p < 0.001). Sleep disturbance was significantly improved with the median of the scores decreased from 8.0 to 2.0 (p < 0.001). These improvements were sustained over a period of up to 6 months. There were no severe adverse events reported. Mild side effects reported were dryness in mucous tissue (5.4%), fatigue (4.8%), and increased appetite (2.7%). Therapy tolerance was reported in 91% of the interviews. Conclusion: Medical cannabis is safe and highly effective for treating neuropathic pain and concomitant sleep disturbance. Keywords: Side effect, Medical cannabis, Neuropathic pain, Cannabinoids, Sleep disturbance
Author(s): Lan Kluwe [a]; Christian Scholze [b]; Lisa Marie Schmidberg [b]; Julian Lukas Wichmann [b]; Mihail Gemkov [b]; Martin Julian Keller [b,c]; Said C. Farschtschi [a] Introduction Neuropathic pain has [...]