학술논문
A rare form of hyperthyroidism leading to the diagnosis of acromegaly: A case report
Document Type
Academic Journal
Author
Source
Experimental and Therapeutic Medicine. October 2023, Vol. 26 Issue 4
Subject
Language
English
ISSN
1792-0981
Abstract
Introduction Acromegaly is a rare disease, usually caused by a pituitary tumor secreting growth hormone (GH), that has an annual incidence rate between 0.2 and 1.1 cases per 100,000 individuals [...]
Acromegaly is a rare disease, usually caused by a pituitary tumor. It typically exhibits slow evolution and can result in numerous complications. In the present case report, the patient presented with hyperthyroidism associated with ophthalmopathy and right nodular goiter. The laboratory tests revealed persistent high levels of phosphorus without an apparent cause. After ruling out common pathologies associated with this finding, a focus was placed on the clinical aspects associated with acromegaly, a rare cause of hyperphosphatemia. Laboratory tests and MRI confirmed the diagnosis. The patient underwent transsphenoidal surgery, but the disease remained active, thus medical treatment was initiated, to a poor initial response. Associated with acromegaly, two distinct thyroid pathologies were diagnosed: Toxic adenoma and Graves' disease. This case highlights the challenges in diagnosing and managing a rare endocrine pathology. Key words: acromegaly, Graves' disease, toxic adenoma, ophthalmopathy, phosphate
Acromegaly is a rare disease, usually caused by a pituitary tumor. It typically exhibits slow evolution and can result in numerous complications. In the present case report, the patient presented with hyperthyroidism associated with ophthalmopathy and right nodular goiter. The laboratory tests revealed persistent high levels of phosphorus without an apparent cause. After ruling out common pathologies associated with this finding, a focus was placed on the clinical aspects associated with acromegaly, a rare cause of hyperphosphatemia. Laboratory tests and MRI confirmed the diagnosis. The patient underwent transsphenoidal surgery, but the disease remained active, thus medical treatment was initiated, to a poor initial response. Associated with acromegaly, two distinct thyroid pathologies were diagnosed: Toxic adenoma and Graves' disease. This case highlights the challenges in diagnosing and managing a rare endocrine pathology. Key words: acromegaly, Graves' disease, toxic adenoma, ophthalmopathy, phosphate