학술논문

Giant adrenal metastasis of malignant melanoma: impact of 18F-FDG PET/CT in early assessment of dramatic response to immunotherapy: case report
Case Report
Document Type
Academic Journal
Source
The Egyptian Journal of Radiology and Nuclear Medicine. December 2023, Vol. 54 Issue 1
Subject
Care and treatment
Positron emission tomography
Ipilimumab
Nivolumab
Immunotherapy
Cancer metastasis -- Care and treatment
Medical schools
Metastasis -- Care and treatment
PET imaging
Medical colleges
Language
English
ISSN
0378-603X
Abstract
Author(s): Forough Kalantari [sup.1] [sup.2], Gregor Schweighofer-Zwink [sup.1], Gundula Rendl [sup.1], Christian Pirich [sup.1], Mohsen Beheshti [sup.1] Author Affiliations: (1) https://ror.org/03z3mg085, grid.21604.31, 0000 0004 0523 5263, Division of Molecular Imaging [...]
Background This case represents one of the largest adrenal metastases in the literature and highlights the importance of accurate imaging in clinical management of patients with advanced malignant melanoma. Case presentation A 67-year-old female with an ulcerated malignant melanoma presented with an asymptomatic 18-cm left adrenal mass on 18F-FDG PET/CT staging. After two cycles of combined systemic immunotherapy, an impressive shrinkage of the adrenal metastatic tumor was observed on 18F-FDG PET/CT imaging. Conclusions The case emphasizes the potential of 18F-FDG PET/CT as a functional imaging modality for accurate staging and precise early assessment of response to immunotherapy. Overall, this report highlights the importance of accurate imaging for the effective management of adrenal metastases in melanoma patients.