학술논문

Paraurachal paraganglioma
Document Type
Academic Journal
Source
IJU Case Reports. September 2022, Vol. 5 Issue 5, p358, 361 p.
Subject
Care and treatment
Embryonic development
Immunohistochemistry
Tumor removal
Language
English
Abstract
Abbreviations & Acronyms Keynote message We report a case of PGL that arose around the urachus and was thought to be derived from the chromaffin cells that migrated to the [...]
Introduction: Paragangliomas (PGLs) are frequently reported around the abdominal aorta; however, are extremely rare near the urachus. Case presentation: A 78‐year‐old woman was referred to the urology department of our hospital for further examination and treatment of a 1.2‐cm tumor in the lower abdominal wall, a tumor excision was then performed. On immunohistochemical staining, the tumor and supporting cells were positive for chromogranin A and the S 100 protein, respectively, and were diagnosed as PGL. The PGL was thought to be derived from chromaffin cells that migrated to the wall of the urachus during embryonic life and remained even after the wall regressed. Conclusion: We report a case of PGL near the urachus that can be explained by the distribution of the sympathetic network around the midline of the lower abdominal wall during embryonic development. Therefore, PGL should be considered in the differential diagnosis of periurachal tumors.