학술논문

A risk score to predict 30-day hospital readmission rate in cirrhotic patients with spontaneous bacterial peritonitis
Document Type
Academic Journal
Source
European Journal of Medical Research. May 12, 2023, Vol. 28 Issue 1
Subject
Medical research
Medicine, Experimental
Bilirubin
Clinics
Liver
Peritonitis -- Risk factors
Liver cirrhosis -- Risk factors
Language
English
ISSN
0949-2321
Abstract
Background and aim There is lack of 30-day hospital readmission prediction score in patients with liver cirrhosis and SBP. The aim of this study is to recognize factors capable of predicting 30-day readmission and to develop a readmission risk score in patients with SBP. Methods This study prospectively examined the 30-day hospital readmission for patients previously discharged with a diagnosis of SBP. Based on index hospitalization variables, a multivariable logistic regression model was implemented to recognize predictors of patient hospital readmission within 30 days. Consequently, Mousa readmission risk score was established to predict 30-day hospital readmission. Results Of 475 patients hospitalized with SBP, 400 patients were included in this study. The 30-day readmission rate was 26.5%, with 16.03% of patients readmitted with SBP. Age [greater than or equal to] 60, MELD > 15, serum bilirubin > 1.5 mg/dL, creatinine > 1.2 mg/dL, INR > 1.4, albumin < 2.5 g/dL, platelets count [less than or equai to] 74 (10.sup.3/dL) were found to be independent predictors of 30-day readmission. Incorporating these predictors, Mousa readmission score was established to predict 30-day patient readmissions. ROC curve analysis demonstrated that at a cutoff value [greater than or equal to] 4, Mousa score had optimum discriminative power for predicting the readmission in SBP with sensitivity 90.6% and specificity 92.9%. However, at cutoff value [greater than or equal to] 6 the sensitivity and specificity were 77.4% and 99.7%, respectively, while a cutoff value [greater than or equal to] 2 had sensitivity of 99.1% and specificity of 31.6%. Conclusions The 30-day readmission rate of SBP was 25.6%. With the suggested simple risk assessment Mousa score, patients at high risk for early readmission can be easily identified so as to possibly prevent poorer outcomes. Keywords: Spontaneous bacterial peritonitis, 30-day readmission rate, Liver cirrhosis
Author(s): Nasser Mousa[sup.1,2], Ahmed Abdel-Razik[sup.1], Sherif Elbaz[sup.3], Mohamed Salah[sup.1], Mohammed Abdelaziz[sup.1], Alaa Habib[sup.4], Ahmed Deib[sup.4], Abdel-Naser Gadallah[sup.5], Niveen El-wakeel[sup.6], Waleed Eldars[sup.6,7], Narmin effat[sup.8], Ola El-Emam[sup.8], Khaled Taha[sup.4], Alaa Elmetwalli[sup.9], Eman [...]