학술논문

High Throughput Sequencing for Clinical Tuberculosis: An Overview
Document Type
Medical procedure overview
Source
Pathogens. November, 2022, Vol. 11 Issue 11
Subject
United States
Language
English
ISSN
2076-0817
Abstract
High throughput sequencing (HTS) can identify the presence of Mycobacterium tuberculosis DNA in a clinical sample while also providing information on drug susceptibility. Multiple studies have provided a context for exploring the clinical application of HTS for TB diagnosis. The workflow challenges, strengths and limitations of the various sequencing platforms, and tools used for analysis are presented to provide a framework for further innovations in the field.
Author(s): Tara E. Ness (corresponding author) [1,2,*]; Andrew DiNardo [2]; Maha R. Farhat [3] 1. Introduction High throughput sequencing (HTS), also known as next generation sequencing (NGS) can identify the [...]