학술논문
Omicron variant of SARS‐CoV‐2, an epidemiologic assessment of pediatric oncology patients in the Bronx
Document Type
Report
Source
Cancer Reports. November 2022, Vol. 5 Issue 11
Subject
Language
English
Abstract
BACKGROUND When children with cancer have a fever in the setting of chemotherapy‐induced neutropenia, they are managed empirically for bacteremia. However, a viral etiology is common and, in many cases, [...]
: Background: Children receiving cytotoxic therapy for cancer have increased risk of infection due to drug‐induced neutropenia and are therefore treated empirically for bacteremia when febrile or ill‐appearing. However, viral infections, which are not frequently life‐threatening, are the most common etiology of febrile episodes and there has been increased effort to differentiate patients who may have a higher risk for adverse outcomes. Case: We performed a retrospective chart review of pediatric oncology patients diagnosed with COVID‐19 between December 20, 2021 and February 22, 2022 during the Omicron (B.1.1.529) surge at The Children's Hospital at Montefiore, a tertiary care center in the Bronx. Conclusion: We found that no patients in our cohort developed respiratory distress, bacteremia, or serious illness after COVID‐19 infection during the Omicron surge. Future studies will aid in understanding the relationship between community‐acquired infections and bacteremia, and this knowledge can then be applied to develop optimal infection prevention clinical care guidelines.
: Background: Children receiving cytotoxic therapy for cancer have increased risk of infection due to drug‐induced neutropenia and are therefore treated empirically for bacteremia when febrile or ill‐appearing. However, viral infections, which are not frequently life‐threatening, are the most common etiology of febrile episodes and there has been increased effort to differentiate patients who may have a higher risk for adverse outcomes. Case: We performed a retrospective chart review of pediatric oncology patients diagnosed with COVID‐19 between December 20, 2021 and February 22, 2022 during the Omicron (B.1.1.529) surge at The Children's Hospital at Montefiore, a tertiary care center in the Bronx. Conclusion: We found that no patients in our cohort developed respiratory distress, bacteremia, or serious illness after COVID‐19 infection during the Omicron surge. Future studies will aid in understanding the relationship between community‐acquired infections and bacteremia, and this knowledge can then be applied to develop optimal infection prevention clinical care guidelines.