학술논문

Structural and Functional Characteristics of Cerebral Arteries as an Explanation for Clinical Syndromes Limited to the Brain
Document Type
Report
Source
Cerebrovascular Diseases. January 1, 2023, Vol. 52 Issue 1, p52, 9 p.
Subject
Arteries -- Physiological aspects
Medical research -- Physiological aspects
Medicine, Experimental -- Physiological aspects
Disease susceptibility -- Risk factors
Blood circulation disorders -- Risk factors
Language
English
ISSN
1015-9770
Abstract
Vascular disease affects many different arterial beds throughout the body. Yet the brain is susceptible to several vascular disorders that either are not found in other parts of the body or when found are much less likely to cause clinical syndromes in other organs. This specific vulnerability of the brain may be explained by structural and functional differences between the vessels of the brain and those of vessels in other parts of the body. In this review, we focus on how cerebrovascular anatomy and physiology may make the brain and its vessels more susceptible to unique vascular pathologies. To highlight these differences, we use our knowledge of five diseases and syndromes that most commonly manifest in the intracranial vasculature. For each, we identify characteristics of the intracranial arteries that make them susceptible to these diseases, while noting areas of uncertainty requiring further research. Keywords: Ischemic stroke, Pathology, Cerebral arteries, Vascular disease, Brain
Author(s): Setareh Salehi Omran [a]; Jose Gutierrez [b]; Jay P. Mohr [b]; Mitchell S.V. Elkind [b,c] Introduction Arteries in the human brain share many features with those of arteries from [...]