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Introduction Prostate cancer (PC) is the most common cancer in men and as such has important consequences for healthcare systems accounting for around 9 billion euros annually in EU. According [...]
Prostate cancer is the most common cancer in men. Diagnosis of prostate cancer poses a significant challenge, due to several different key parameters that need to be evaluated, such as age, history of prostate specific antigen (PSA), clinical examination and more recently magnetic resonance imaging (MRI). The current diagnostic pathway for prostate cancer has resulted in overdiagnosis and overtreatment as well as underdiagnosis and missed diagnoses in many men. Multiparametric MRI (mp-MRI) of the prostate has been identified as a test that could alleviate these diagnostic errors. Before prostate cancer treatment pathological confirmation is mandatory. Prostate biopsy is an invasive procedure with rare but not negligible potential complications. There are several methods of prostate biopsy of which most common are systemic or planar prostate biopsy and cognitive or targeted MRI-guided prostate biopsy. Multiparametric MRI has demonstrated better accuracy and reproducibility in detecting, locating and evaluating prostate cancer and also sparing some men unnecessary biopsies. Recent studies have shown a mpMRI benefit for better procedure planning regarding prostate cancer location, extent of disease and length of the urethra. There are still some challenges ahead, such as ensuring high-quality execution and reporting of mpMRI and ensuring that this diagnostic pathway is cost-effective. According to the latest urological clinical guidelines mpMRI became fundamental tool in management of prostate cancer. The aim of this study is to give a brief insight in use of mpMRI in prostate cancer diagnosis and treatment Key words:prostate cancer, mpMRI, prostate biopsy, prostate cancer diagnosis and treatment Rakprostate najcesci je karcinom u muskaraca. Dijagnoza raka prostate predstavlja znacajan izazov zbog nekoliko razlicitih kljucnih parametara koje je potrebno procijeniti, kao sto su dob, povijest prostata specificnog antigena (PSA), klinicki pregled i u novije vrijeme multiparametrijski MRI (mp-MRI).Trenutna dijagnostika raka prostate rezultirala je prekomjernom dijagnostikom i lijecenjem, kao i poddijagnozom i propustenom dijagnozom kod mnogih muskaraca. Multiparametrijski MRI prostate identificiran je kao test koji bi mogao ublaziti ove pogreske. Prije lijecenja raka prostate obavezna je patoloska potvrda. Biopsija prostate je invazivan postupak s rijetkim, ali ne i zanemarivim potencijalnim komplikacijama. Postoji nekoliko metoda biopsije prostate od kojih su najcesce sistemska ili planarna biopsija prostate i kognitivna ili ciljana biopsija prostate vodena MRI-om. Mp-MRI pokazao je bolju tocnost i reproducibilnost u otkrivanju, lociranju i procjeni raka prostate, a takoder je postedio neke muskarace nepotrebne biopsije. Nedavne studije pokazale su korist mpMRI-e za bolje planiranje zahvata s podacima o lokaciji raka prostate, opsegu bolesti i duljini uretre. Pred nama sujos neki izazovi, poput osiguravanja visokokvalitetne izvedbe i izvjescivanja o mpMRI-u te osiguravanja da je ovaj dijagnosticki put isplativ. Prema najnovijim uroloskim klinickim smjernicama mpMRI je postao temeljni alat u lijecenju raka prostate. Cilj ove studije je dati kratak uvid u upotrebu mpMRI-e u dijagnostici i lijecenju raka prostate Kljucne rijeci: rak prostate, mpMRI, biopsija prostate, dijagnostika i lijecenje raka prostate