학술논문
Twenty-Four-Month OCTA Assessment in Diabetic Patients Undergoing Fixed-Interval Intravitreal Aflibercept Therapy
Document Type
Clinical report
Author
Source
Ophthalmic Surgery, Lasers, and Imaging Retina. August, 2020, Vol. 51 Issue 8, p448, 8 p.
Subject
Language
English
ISSN
2325-8160
Abstract
BACKGROUND AND OBJECTIVE: Evaluate capillary perfusion density (CPD) in patients with diabetic macular edema (DME) undergoing fixed intravit-real aflibercept injections (IAI) through 24 months. PATIENTS AND METHODS: Prospective, interventional, single-arm study enrolling 20 patients with persistent DME. Patients received IAI every 4 weeks until DME resolution followed by extension to every 8 weeks. Optical coherence tomography angiography was obtained at baseline, 6, 12, and 24 months. RESULTS: Sixteen of 20 eyes completed the study. Baseline mean central subfield thickness was 420 µm, which improved to 251 µm (P CONCLUSION: Superficial and deep CPD decreased despite fixed IAI through 24 months. [Ophthalmic Surg Lasers Imaging Retina. 2020;51:448–455.]
Introduction Prevalence of diabetic retinopathy (DR) in the United States is estimated at 34.6% (93 million people), and 10.2% (28 million) have vision threatening complications. (1,2) The presence of diabetic [...]
Introduction Prevalence of diabetic retinopathy (DR) in the United States is estimated at 34.6% (93 million people), and 10.2% (28 million) have vision threatening complications. (1,2) The presence of diabetic [...]