학술논문
Assessing the epidemiology and seasonality of influenza among children under two hospitalized in Amman, Jordan, 2010‐2013
Document Type
Report
Author
Source
Influenza and Other Respiratory Viruses. November 11, 2020, Vol. 15 Issue 2, p284, 9 p.
Subject
Language
English
ISSN
1750-2640
Abstract
BACKGROUND Acute respiratory infections (ARI) are the leading cause of morbidity and mortality of children under 5 years outside the neonatal period.[sup.1] The majority of ARIs are viral in origin, [...]
: Background: The disease burden of influenza‐associated hospitalizations among children in Jordan is not well established. We aimed to characterize hospitalizations attributed to influenza in a pediatric population. Methods: We conducted a cross‐sectional study from our viral surveillance cohort in children under 2 years hospitalized with acute respiratory symptoms and/or fever from March 2010 to March 2013. We collected demographic and clinical characteristics, and calculated the frequency of children who met the severe acute respiratory illness (SARI) criteria. Nasal specimens were tested using real‐time reverse transcriptase polymerase chain reaction to detect influenza A, B, or C. Further subtyping for influenza A‐positive isolates was conducted. Results: Of the 3168 children enrolled in our study, 119 (4%) were influenza‐positive. Influenza types and subtypes varied by season but were predominantly detected between December and February. Codetection of multiple respiratory pathogens was identified in 58% of children with the majority occurring among those Conclusions: Influenza was an important cause of acute respiratory illness in children under 2 years. Children
: Background: The disease burden of influenza‐associated hospitalizations among children in Jordan is not well established. We aimed to characterize hospitalizations attributed to influenza in a pediatric population. Methods: We conducted a cross‐sectional study from our viral surveillance cohort in children under 2 years hospitalized with acute respiratory symptoms and/or fever from March 2010 to March 2013. We collected demographic and clinical characteristics, and calculated the frequency of children who met the severe acute respiratory illness (SARI) criteria. Nasal specimens were tested using real‐time reverse transcriptase polymerase chain reaction to detect influenza A, B, or C. Further subtyping for influenza A‐positive isolates was conducted. Results: Of the 3168 children enrolled in our study, 119 (4%) were influenza‐positive. Influenza types and subtypes varied by season but were predominantly detected between December and February. Codetection of multiple respiratory pathogens was identified in 58% of children with the majority occurring among those Conclusions: Influenza was an important cause of acute respiratory illness in children under 2 years. Children