학술논문
Lung function and exercise capacity 6 months after hospital discharge for critical COVID-19
Document Type
Report
Author
Source
BMC Pulmonary Medicine. June 22, 2022, Vol. 22 Issue 1
Subject
Language
English
ISSN
1471-2466
Abstract
Author(s): Salla Kattainen[sup.1,2,9] , Anna Lindahl[sup.2,3] , Tuula Vasankari[sup.3,4] , Henriikka Ollila[sup.1,2] , Kirsi Volmonen[sup.5] , Päivi Piirilä[sup.2,6] , Paula Kauppi[sup.7] , Juuso Paajanen[sup.7] , Hanna-Riikka Kreivi[sup.7] , Linda Ulenius[sup.8] [...]
Background The significant morbidity caused by COVID-19 necessitates further understanding of long-term recovery. Our aim was to evaluate long-term lung function, exercise capacity, and radiological findings in patients after critical COVID-19. Methods Patients who received treatment in ICU for COVID-19 between March 2020 and January 2021 underwent pulmonary function tests, a 6MWD and CXR 6 months after hospital discharge. Results A restrictive ventilatory defect was found in 35% (23/65) and an impaired diffusing capacity in 52% (32/62) at 6 months. The 6-minute walk distance was reduced in 33% (18/55), and 7% (4/55) of the patients had reduced exercise capacity. Chest X-ray was abnormal in 78% (52/67) at 6 months after hospital discharge. Conclusion A significant number of patients had persisting lung function impairment and radiological abnormalities at 6 months after critical COVID-19. Reduced exercise capacity was rare. Keywords: COVID-19, ARDS, Critical care, Lung function, Exercise capacity
Background The significant morbidity caused by COVID-19 necessitates further understanding of long-term recovery. Our aim was to evaluate long-term lung function, exercise capacity, and radiological findings in patients after critical COVID-19. Methods Patients who received treatment in ICU for COVID-19 between March 2020 and January 2021 underwent pulmonary function tests, a 6MWD and CXR 6 months after hospital discharge. Results A restrictive ventilatory defect was found in 35% (23/65) and an impaired diffusing capacity in 52% (32/62) at 6 months. The 6-minute walk distance was reduced in 33% (18/55), and 7% (4/55) of the patients had reduced exercise capacity. Chest X-ray was abnormal in 78% (52/67) at 6 months after hospital discharge. Conclusion A significant number of patients had persisting lung function impairment and radiological abnormalities at 6 months after critical COVID-19. Reduced exercise capacity was rare. Keywords: COVID-19, ARDS, Critical care, Lung function, Exercise capacity